Advances in pharmacological effects of ginsenoside on Alzheimer's disease
- Author:
Yan-Tao YANG
1
;
Jia-Zhu ZHAO
1
;
Jia-Mei XIAO
1
;
Yan YANG
1
;
Gang PEI
1
;
Nai-Hong CHEN
1
;
Yan-Tao YANG
2
;
Gang PEI
2
;
Nai-Hong CHEN
2
;
Yan-Tao YANG
3
;
Nai-Hong CHEN
4
Author Information
- Publication Type:Journal Article
- Keywords: Alzheimer' s disease; effect; ginsenoside; learning and memorizing; mechanism of action; pathway
- From: Chinese Pharmacological Bulletin 2021;37(12):1638-1643
- CountryChina
- Language:Chinese
- Abstract: Alzheimer's disease (AD) has become one of the major diseases that plague human health and seriously affect the quality of life of patients. Up to present there is no specific treatment drug for Alzheimer' s disease, which still needs research and development. Ginseng is an important traditional Chinese medicine in the prescription for treating of Alzheimer's disease, which contains saponins, polysaccharides, volatile components, proteins, vitamins, amino acids and other compounds. Saponins are the main active components, which have a good effect on improving learning and memory ability and preventing AD. In this paper, the effect and the mechanism of ginsenosides for treating AD are reviewed in order to provide ideas for developing ginsenosides into drugs with better clinical compliance and more effective treatment of AD.
