Korean Guidelines for Diagnosis and Treatment of Tuberculosis in Children and Adolescents.
- Author:
Kyong Min CHOI
1
;
Nam Hee KIM
;
Dong Ho KIM
;
Yae Jean KIM
;
Jong Hyun KIM
;
Sung Hee OH
;
Byung Wook EUN
;
Soo Young LEE
;
Taek Jin LEE
;
Jin Kyong CHUN
;
Jung Yun HONG
Author Information
1. Joint Committee for the Development of Korean Guidelines for Tuberculosis, Korea. ckm2001@hanmail.net
- Publication Type:Review
- Keywords:
Tuberculosis;
Children;
Adolescents
- MeSH:
Adolescent;
Adult;
Child;
Humans;
Incidence;
Korea;
Latent Tuberculosis;
Skin Tests;
Tuberculin;
Tuberculosis;
Tuberculosis, Miliary
- From:Korean Journal of Pediatric Infectious Diseases
2011;18(1):1-14
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Tuberculosis is a disease with high morbidity and mortality in children worldwide. Despite the decrease in the incidence of tuberculosis in Korea, more than 30,000 new patients are diagnosed each year. Active tuberculosis is less frequent in children compared to adults but the risk of miliary tuberculosis and CNS tuberculosis is much higher. The diagnosis of tuberculosis in children and adolescents is difficult due to the nonspecific symptoms upon presentation. Diagnostic work up is based on the confirmation of tuberculosis infection by tuberculin skin test, abnormal radiologic findings, and contact with an adult with active tuberculosis. Anti-tuberculosis medications are prescribed according to the drug susceptibility of the index patient. Latent tuberculosis infection plays an important role in adult tuberculosis by reactivation. Thus, it is critical to accurately diagnose latent tuberculosis in children to prevent reactivation in adulthood. Korean guidelines for diagnosis and treatment of tuberculosis in children and adolescents provide evidence based recommendations in the optimal diagnosis and treatment for active and latent tuberculosis in children and adolescents based on the current Korean situation.
