The protective effect of cyclosporine A on daunorubicin injured H9c2 cardiomyoblasts

Author: Zhi-Juan WU ¹ ; Shi-Zhen CHEN ¹ ; Li-Xia XU ¹ ; Rui-Lan HE ¹ ; Hai-Xia JIAO ¹ ; Mo-Jun LIN ¹ ; Zhi-Juan WU ² ; Shi-Zhen CHEN ² ; Li-Xia XU ² ; Rui-Lan HE ² ; Hai-Xia JIAO ² ; Mo-Jun LIN ² ; Shi-Zhen CHEN ³
Author Information

1. The Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Fujian Medical University
2. Dept of Physiology and Pathophysiology, The School of Basic Medical Sciences, Fujian Medical University
3. Dept of Nephrology, The Third People's Hospital of Hubei Province
Publication Type:Journal Article
Keywords: apoptosis; CaN; cyclosporine A; daunorubicin; H9c2 cardiomyoblasts; myocardial injury; NFAT
From: Chinese Pharmacological Bulletin 2021;37(7):972-978
CountryChina
Language:Chinese
Abstract: Aim To study the protective effect of cyclosporine A (CsA) on daunorubicin (DNR) injured H9c2 cardiomyoblasts. Methods H9c2 cells were pre-treated with CsA for 2 hours, then co-cultured with 1 μmol · L