Research progress on relationship between medial prefrontal cortex and neuropsychiatric diseases
10.3969/j.issn.1001-1978.2021.06.002
- Author:
Si-Hao QI
1
;
Hao HONG
1
Author Information
1. Dept of Pharmacology, School of Pharmacy, China Pharmaceutical University
- Publication Type:Journal Article
- Keywords:
medial prefrontal cortex;
molecular expression;
neural circuits;
neuropsychiatric disorders
- From:
Chinese Pharmacological Bulletin
2021;37(6):745-748
- CountryChina
- Language:Chinese
-
Abstract:
The medial prefrontal cortex (mPFC) received input from multiple cortical and subcortical areas, and integrated relevant information to other cortical and subcortical areas. mPFC play an important role in neuropsychiatric events such as depression, anxiety, schizophrenia, Alzheimer's and Parkinson's disease, as well as in neuropsychiatric processes such as cognitive, social, and reward behaviors. This article reviews the role and molecular mechanism of the neural circuitry in the medial prefrontal cortex in neuropsychiatric diseases, especially the recent research progress.
