The neuroprotective effect of rhubarb on MCAO model rats
- Author:
Chun-Xiao SUN
1
;
Jia-Hui HUANG
1
;
Li QIAO
1
;
Jun-Jie LIU
1
;
Yu-Heng TANG
1
;
A-Juan XU
1
;
Jing-Wen NIE
1
;
Si-Ying HUANG
1
;
Rui LUO
1
;
Ze-Lin YANG
1
;
Wen-Fang LAI
1
;
Gui-Zhu HONG
1
Author Information
- Publication Type:Journal Article
- Keywords: BDNF; Egrs; MCAO; neuroprotection; NGF; rhubarb extract
- From: Chinese Pharmacological Bulletin 2021;37(4):584-589
- CountryChina
- Language:Chinese
- Abstract: Aim To study the neuroprotective effect of rhubarb extract on MCAO model rats and explore its mechanism of action. Methods Forty-five SPF male Sprague-Dawley rats were randomly divided into sham group, MCAO group, and MCAO + rhubarb group. MCAO model was prepared by silk plug method, and rhubarb extract was administered at a concentration of 200 mg · kg
