Application of network pharmacology in treatment of autoimmune diseases with traditional Chinese medicine
10.3969/j.issn.1001-1978.2021.03.006
- Author:
Jia-Long TANG
1
;
Li-Chao ZHANG
1
;
Li ZHOU
2
;
Zu-Yue SUN
2
Author Information
1. Dept of Parmacy Shanghai Municipal Hospital of Traditional, Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
2. School of Pharmacy, Fudan University
- Publication Type:Journal Article
- Keywords:
Autoimmune diseases;
Network pharmacology;
Psoriasis;
Rheumatoid arthritis;
Systemic lupus erythematosus;
Traditional Chinese medicine
- From:
Chinese Pharmacological Bulletin
2021;37(3):323-327
- CountryChina
- Language:Chinese
-
Abstract:
The pathogenesis of autoimmune disease is complex, lacking in specific markers and new therapeutic targets. Traditional Chinese medicine (T C M) is effective in treating chronic complex diseases such as autoimmune diseases, but the specific mechanism of action remains unclear. The core idea of network pharmacology has much in common with the overall philosophy of TCM. As a new discipline, it provides a new research mode for TCM to transform from empirical medicine to evidence-based medicine. Network pharmacology has been applied in many fields of research, but its application in a certain kind of disease is rarely reviewed. Through searching domestic and foreign literature, this paper reviews the application of network pharmacology in the prevention and treatment of rheumatoid arthritis, psoriasis, systemic lupus erythematosus with traditional Chinese medicine and identification of related biological targets.
