Research advances in animal models of diabetic retinopathy
10.3969/j.issn.1001-1978.2021.03.001
- Author:
Yun LUO
1
;
Gui-Bo SUN
1
;
Xiao-Bo SUN
1
;
Wen-Xiu GE
2
Author Information
1. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences
2. School of Pharmacy, Engineering Research Center for Medicine, Harbin University of Commerce
- Publication Type:Journal Article
- Keywords:
Diabetic retinopathy;
Experimental animal models;
Gene type;
Induced phenotype;
Microaneurysm;
Research advances
- From:
Chinese Pharmacological Bulletin
2021;37(3):297-301
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic retinopathy (DR) is one of the microvascular complications of diabetes. At present, the pathogenesis of DR is obscure and drugs can not meet clinical needs, however. Experimental animal model of DR is an effective tool to study its pathogenic mechanism and evaluate drug efficacy. In this paper, the research progress of experimental animal models of DR has been-reviewed in recent years, mainly using mice, zebrafish, and other experimental animals, which can be divided into two categories: induced type and genotype, according to the inducer.
