The electrophysiological remodeling of atrial myocytes of type 1 diabetic mice and effects of AGE

Dan-lin Zheng; Li Zhang; Meng-yuan Zhou; Sui-min LI; Xiao-yue Qin; Hai-dan Liang; Chun-yu Deng; Dan-lin Zheng; Pei-ming Liu; Li Zhang; Meng-yuan Zhou; Peng Zeng; Sui-min LI; Xiao-yue Qin; Hai-dan Liang; Su-juan Kuang; Hui Yang; Fang Rao; Chun-yu Deng; Dan-lin Zheng; Pei-ming Liu; Li Zhang; Meng-yuan Zhou; Peng Zeng; Sui-min LI; Xiao-yue Qin; Hai-dan Liang; Su-juan Kuang; Hui Yang; Fang Rao; Chun-yu Deng; Pei-ming Liu; Peng Zeng; Chun-yu Deng; Pei-ming Liu; Peng Zeng; Su-juan Kuang; Hui Yang; Fang Rao; Chun-yu Deng

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The electrophysiological remodeling of atrial myocytes of type 1 diabetic mice and effects of AGE

Author: Dan-Lin ZHENG ¹ ; Li ZHANG ¹ ; Meng-Yuan ZHOU ¹ ; Sui-Min LI ¹ ; Xiao-Yue QIN ¹ ; Hai-Dan LIANG ¹ ; Chun-Yu DENG ¹ ; Dan-Lin ZHENG ² ; Pei-Ming LIU ² ; Li ZHANG ² ; Meng-Yuan ZHOU ² ; Peng ZENG ² ; Sui-Min LI ² ; Xiao-Yue QIN ² ; Hai-Dan LIANG ² ; Su-Juan KUANG ² ; Hui YANG ² ; Fang RAO ² ; Chun-Yu DENG ² ; Dan-Lin ZHENG ³ ; Pei-Ming LIU ³ ; Li ZHANG ³ ; Meng-Yuan ZHOU ³ ; Peng ZENG ³ ; Sui-Min LI ³ ; Xiao-Yue QIN ³ ; Hai-Dan LIANG ³ ; Su-Juan KUANG ³ ; Hui YANG ³ ; Fang RAO ³ ; Chun-Yu DENG ³ ; Pei-Ming LIU ⁴ ; Peng ZENG ⁴ ; Chun-Yu DENG ⁴ ; Pei-Ming LIU ⁵ ; Peng ZENG ⁵ ; Su-Juan KUANG ⁵ ; Hui YANG ⁵ ; Fang RAO ⁵ ; Chun-Yu DENG ⁵
Author Information

1. School of Biological Science and Engineering, South China University of Technology
2. Key Lab of Clinical Pharmacology, Medical Research Dept
3. Hospital Guangdong Academy of Medical Sciences
4. School of Medicine, South China University of Technology
5. Dept of Cardiology, Guangdong Institute of Cardiovascular Diseases
Publication Type:Journal Article
Keywords: AGE; atrial myocytes; electrical remodeling; ion channels; STZ; type 1 diabetes
From: Chinese Pharmacological Bulletin 2021;37(1):90-98
CountryChina
Language:Chinese
Abstract: Aim To explore type 1 diabetes mice and the advance glycation end products (AGE) involved in electrical remodeling of atrial myocytes. Methods The diabetic mouse model was induced by intraperitoneal injection of STZ; action potential duration, and the current density of I