- Author:
Chen-Zhen XU
1
;
Ning LI
1
;
Qing GENG
1
Author Information
- Publication Type:Journal Article
- Keywords: acute lung injury; mechanism; natural polyphenol; quercetin; regulated cell death; resveratrol
- From: Chinese Pharmacological Bulletin 2022;38(10):1452-1456
- CountryChina
- Language:Chinese
- Abstract: Acute lung injury(ALI)is a critical respiratory disorder characterized by progressive respiratory failure with high morbidity and mortality.In addition to respiratory support, ALI still lacks effective medications.Natural polyphenol, a class of natural compounds widely found in human daily food, have been proven to possess anti-inflammatory, anti-oxidant, regulating cell death, anti-pathogen infection, and exert therapeutic effects on ALI.This article reviews the pathogenesis of ALI and the mechanism of natural polyphenols in the treatment of ALI, aiming to provide a new direction for the treatment of ALI.