A Case of Solitary Bone Plasmacytoma Presenting with Erythematous Swelling of the Upper Eyelid.
- Author:
Kuk Hyoe KIM
1
;
Dong Eun OH
;
Yoon Duck KIM
Author Information
1. Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. ydkim@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
Solitary bone plasmacytoma
- MeSH:
Biopsy;
Bone Marrow;
Diagnosis;
Exophthalmos;
Eyelids*;
Female;
Follow-Up Studies;
Humans;
Immunoelectrophoresis;
Middle Aged;
Multiple Myeloma;
Orbit;
Plasmacytoma*;
Prognosis;
Sphenoid Bone;
Tomography, X-Ray Computed
- From:Journal of the Korean Ophthalmological Society
2007;48(5):731-736
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To demonstrate a rare case of orbital solitary bone plasmacytoma that presented with erythematous swelling of the upper eyelid. METHODS: A 64-year-old woman presented with a erythematous swelling of the right upper eyelid that persisted for 8 months prior to examination. There were 3 mm of proptosis in the right eye on ophthalmologic examination and an orbital tumor was detected on computed tomography (CT) scan, infiltrating the intracranial space and the sphenoid bone. Therefore, we performed incisional biopsy through the right upper eyelid. RESULTS: Histopathologic examination revealed the tumor to be a plasmacytoma (lambda light chain-type) and all the systemic work-ups (serologic and urinary protein immunoelectrophoresis, bone marrow biopsy, radiologic examination) to rule out multiple myeloma were negative. Because of these factors, a diagnosis of solitary bone plasmacytoma was made. Radiation therapy (5,000 Gy/25 fractions) was performed over 5 weeks and the size of the tumor was found to have markedly decreased on a follow-up CT scan. CONCLUSIONS: Solitary bone plasmacytoma is rare and has variable prognoses. This condition should be considered when the presenting symptom is eyelid swelling and proptosis.
