Advances in research of polysaccharides on inflammatory diseases and gut microbiota

Yu-zhe Huang; Qian-zhen WU; Hao Chen; Kun-feng Zhang; Jie-lin Chen; Yan Chen; Teng-fei XU; Da-xiang LI

Return

Advances in research of polysaccharides on inflammatory diseases and gut microbiota

Author: Yu-Zhe HUANG ¹ ; Qian-Zhen WU ¹ ; Hao CHEN ¹ ; Kun-Feng ZHANG ¹ ; Jie-Lin CHEN ¹ ; Yan CHEN ¹ ; Teng-Fei XU ² ; Da-Xiang LI ³
Author Information

1. Key Laboratory of Ecological Engineering and Biotechnology of Anhui Province, School of Life Science, Anhui University
2. Nanjing Kang Zhi Chun Biological Technology Co., Ltd
3. State Key Laboratory of Tea Plant Biology and Utilization, School of Tea and Food Sciences and Technology, Anhui Agricultural University
Publication Type:Journal Article
Keywords: degradation mechanism; gut microbiota; polysaccharides; prebiotics; regulating effect
From: Chinese Pharmacological Bulletin 2022;38(11):1601-1606
CountryChina
Language:Chinese
Abstract: Gut microbiota is a bridge between the metabolism and health state of the host,which plays a very important role in maintaining homeostasis. Natural polysaccharides,widely existed in nature,are a kind of biological macromolecules with prebiotics effects,which can improve a degree of physiological status by selectively changing the gut microbiota structure and function,enhancing the content of short chain fatty acids(SCFAs)and decreasing the level of inflammatory cytokines. In addition,the majority of polysaccharides can be degraded by gut microbiota to enhance their bioavailability and to promote the health state of the host. In this paper we discuss the interaction among polysaccharides and gut microbiotanatural,degradation mechanism and review gut microbiota as a target in the treatment of metabolic diseases,so as to provide future prospects of natural polysaccharides as " prebiotics " functional factors in the field of biological medicine and health products.