Effect of menthol, a transient receptor potential melastatin-8 channel activator, on pulmonary arterial hypertensive rats
- Author:
Hao-Heng GTU
1
;
Zhuang LI
1
;
Jian-Qin YANG
1
;
Wen-Bin FENG
1
;
Xiao-Qing LIU
1
;
Zi-Jian ZHAO
1
;
Yun-Ping MU
1
;
Fang-Hong LI
1
;
Bin LI
Author Information
- Publication Type:Journal Article
- Keywords: calcium channel; menthol; pulmonary arterial hypertension; right ventricular hypertrophy; transient receptor potential melastatin-8; treatment
- From: Chinese Pharmacological Bulletin 2023;39(4):700-706
- CountryChina
- Language:Chinese
- Abstract: Aim To investigate the effects of menthol, a transient receptor potential melastatin-8 channel activator, on treating pulmonary arterial hypertension (PAH) in PAH model rats caused by monocrotaline (MCT). Methods Male Sprague-Dawley rats were divided into six groups randomly (control group, MCT group, MCT + menthol 1 mg • kg
