Research progress of diabetic renal fibrosis
- Author:
Na SONG
1
;
Min LUO
1
;
Peng WANG
1
;
Rong HUANG
1
;
Lve-Li WANG
1
;
Ling ZHANG
1
;
Wei-Min YANG
1
;
Sha WU
2
;
Yun-Ke SHI
3
;
Yi-Mine MA
3
Author Information
- Publication Type:Journal Article
- Keywords: diabetic nephropathy; molecular mechanism; pathological mechanism; renal fibrosis; research progress; therapeutic targets
- From: Chinese Pharmacological Bulletin 2023;39(7):1222-1227
- CountryChina
- Language:Chinese
- Abstract: Diabetic nephropathy (DN) is one of the most common and serious microvascular complications in patients with diabetes mellitus. Diabetic renal fibrosis ( DRF) is a major pathological change in the development of DN. In recent years the incidence of renal fibrosis (RF) has remained high. For diabetic patients, RF may expose them to kidney transplantation or even death, which brings a great burden to themselves and their families. Therefore, learning the pathogenesis and the current treat ment status of DRF is crucial for the treatment of the disease and the development of new drugs. Here we review the general situa¬tion of DN, the general situation, molecular mechanism, and the treatment of DRF,looking forward to providing a reference for the research and treatment of DRF.
