Review of research progress on neurotransmitter function and depression

Jiao Yao; Yan-tao Yang; Qi-di AL; Mei-yu Lin; Yang Sun; Jun-peng Long; Song-wei Yang; Nai-hong Chen; Nai-hong Chen

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Review of research progress on neurotransmitter function and depression

Author: Jiao YAO ¹ ; Yan-Tao YANG ¹ ; Qi-Di AL ¹ ; Mei-Yu LIN ¹ ; Yang SUN ¹ ; Jun-Peng LONG ¹ ; Song-Wei YANG ¹ ; Nai-Hong CHEN ¹ ; Nai-Hong CHEN ²
Author Information

1. Hunan Engineering Technology Center of Standardization and Function of Chinese Herbal Decoction Pieces, College of Pharmacy, Hunan University of Chinese Medicine
2. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College
Publication Type:Journal Article
Keywords: 5-HT; depression; dopamine; GABA; glutamate; neurotransmitters; norepineph-rine
From: Chinese Pharmacological Bulletin 2023;39(7):1217-1221
CountryChina
Language:Chinese
Abstract: Depression is one of the most common psychiatric disorders with high prevalence, disability and relapse rates, and its etiology and pathogenesis are complex and still not fully understood. Neurotransmitters play a key role in maintaining chemical homeostasis in brain, and many studies have shown a strong link between neurotransmitters and the development and treatment of depression in recent years. Therefore, studying the neurotransmitters associated with depression has the potential to provide research targets and ideas for the pathogenesis and treatment strategies of depression. This paper reviews the recent domestic and foreign research results on neurotransmitter function and the pathogenesis of depression, aiming to analyze the in-depth relationship between neurotransmitter function and the pathogenesis of depression, and provide research ideas for the follow-up ex-ploration of the pathogenesis and diagnosis and treatment strategies of depression.