Effect of miR-124a on oxidative stress injury of pancreatic tissue in type 2 diabetic mice

Author: Yi-Ren CHEN ¹ ; Ming CHEN ¹ ; Ren-Chuan TAO ¹ ; Tao LIANG ¹ ; Yi-Ren CHEN ² ; Ming CHEN ² ; Ren-Chuan TAO ² ; Tao LIANG ² ; Xiao-Hui XU ³
Author Information

1. Dept of Periodontal Mucosa, Affiliated Stomatological Hospital, Guangxi Medical University
2. Guangxi Health Commission Key Laboratory of Prevention and Treatment for Oral Infectious Diseases
3. Dept of Pharmacy, Affiliated Tumor Hospital of Guangxi Medical University
Publication Type:Journal Article
Keywords: CAT; miR-124a; Mn-SOD; oxidative stress; ROS; type 2 diabetes
From: Chinese Pharmacological Bulletin 2023;39(8):1493-1499
CountryChina
Language:Chinese
Abstract: Aim To investigate the effect of miR-124a on oxidative stress injury and β-cell function of pancreas in type 2 diabetic mice. Methods The wild-type C57BL/6 mice and the C57BIV6 mice with low expression of miR-124a were randomly divided into two groups, namely wild-type control (WT Con), miR-124a