Artesunate inhibits development of breast cancer cells via affecting expression of Skp2 and CDKN1A

Author: Li-Ting SUN ¹ ; Guan-Tong SHEN ¹ ; Fei ZHU ¹ ; Jing KANG ¹ ; Jing YUE ¹ ; Ru-Yi SHI ¹ ; Xiao-Ling HU ² ; Nan QIN ³ ; Ke LIAN ⁴ ; Jing KANG ⁴ ; Jing YUE ⁴
Author Information

1. Dept of Medical Cell Biology and Genetics, Shanxi Medical University
2. Dept of Pharmacology, Shanxi Medical University
3. College of Pharmaceutical and Food Engineering, Shanxi University of Chinese Medicine
4. Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University
Publication Type:Journal Article
Keywords: artesunate; breast cancer; cell apoptosis; cell cycle; cell invasion; cell migration; cell proliferation
From: Chinese Pharmacological Bulletin 2023;39(9):1675-1681
CountryChina
Language:Chinese
Abstract: Aim To explore the effect of artesunate (ART) on the function of breast cancer cells during the progression of breast cancer and the possible mechanism of action. Methods MCF-7 (30 μmol • L-