Application and prospect of drug discrimination in field of drug abuse
- Author:
Dan FU
1
;
Qing-Xiao HONG
1
;
Jun GU
1
;
Ze-Min XU
1
;
Ding-Ding ZHUANG
1
;
Wen-Jin XU
1
;
Hui-Fen LIU
1
;
Wen-Hua ZHOU
1
Author Information
- Publication Type:Journal Article
- From: Chinese Pharmacological Bulletin 2023;39(9):1623-1627
- CountryChina
- Language:Chinese
- Abstract: Drug discrimination is a behavioral pharmacological technique to study the discriminative stimulus effects of drug. Currently drug discrimination has been widely used in preclinical drug development of CNS drugs, the most extensive of which is psychodependent research in the field of drug abuse. This review describes in general the basic principles of drug discrimination, preliminarily elaborates on the relevant characteristics and applications of the subjective effects, time-course effect, stereo specificity, individual differences, and receptor mechanisms, and its development prospects for hallucinogens and cannabis drugs are also presented.
