Research progress of MicroRNA in hypertension and its target organ damage

Author: Jing XU ¹ ; Qian-Qian CHEN ¹ ; Ming-Shuang HOU ¹ ; Hong-Ying LYU ¹ ; Guan-Jun JIA ¹ ; Yu-Shun KOU ¹ ; Lin YI ¹ ; Jing XU ² ; Qian-Qian CHEN ² ; Ming-Shuang HOU ² ; Hong-Ying LYU ² ; Guan-Jun JIA ² ; Yu-Shun KOU ² ; Lei ZHAO ³
Author Information

1. College of Integrated Chinese and Western Medicine, Gansu University of Traditional Chinese Medicine
2. Gansu Provincial Key Laboratory of TCM Prevention and Treatment of Chronic Diseases
3. College of Pharmacy, Gansu University of Traditional Chinese Medicine
Publication Type:Journal Article
Keywords: exosome; hypertension; mechanism of action; miRNA; research progress; treatment
From: Chinese Pharmacological Bulletin 2023;39(10):1824-1828
CountryChina
Language:Chinese
Abstract: Hypertension is a risk factor for a variety of cardiovascular diseases, which is an important public health problem in the world today. MiRNAs are a class of highly conserved non-coding small RNAs. In recent years, studies have found that miRNAs are involved in the occurrence and development of hypertension through a variety of ways, causing damage to the important target organs of hypertension, such as heart, brain and kidney. This article reviews the research progress of miRNA in hypertension in recent years, in order to clarify its role in the process of hypertension and target organ damage, and provide ideas for exploring new therapeutic targets of hypertension.