Gold thread implantation promotes hair growth in human and mice.
10.5625/lar.2017.33.4.291
- Author:
Jong Hwan KIM
1
;
Eun Young CHO
;
Euna KWON
;
Woo Ho KIM
;
Jin Sung PARK
;
Yong Soon LEE
;
Jun Won YUN
;
Byeong Cheol KANG
Author Information
1. Goldhappy Mirae Aesthetic Clinic, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Gold thread;
hair loss;
hair growth
- MeSH:
Animals;
Biology;
Collagen;
Connective Tissue;
Hair Follicle;
Hair Removal;
Hair*;
Humans*;
Lifting;
Mice*;
Minoxidil;
Polyglycolic Acid;
Proliferating Cell Nuclear Antigen;
Regeneration;
Skin
- From:Laboratory Animal Research
2017;33(4):291-297
- CountryRepublic of Korea
- Language:English
-
Abstract:
Thread-embedding therapy has been widely applied for cosmetic purposes such as wrinkle reduction and skin tightening. Particularly, gold thread was reported to support connective tissue regeneration, but, its role in hair biology remains largely unknown due to lack of investigation. When we implanted gold thread and Happy Lift™ in human patient for facial lifting, we unexpectedly found an increase of hair regrowth in spite of no use of hair growth medications. When embedded into the depilated dorsal skin of mice, gold thread or polyglycolic acid (PGA) thread, similarly to 5% minoxidil, significantly increased the number of hair follicles on day 14 after implantation. And, hair re-growth promotion in the gold threadimplanted mice were significantly higher than that in PGA thread group on day 11 after depilation. In particular, the skin tissue of gold thread-implanted mice showed stronger PCNA staining and higher collagen density compared with control mice. These results indicate that gold thread implantation can be an effective way to promote hair re-growth although further confirmatory study is needed for more information on therapeutic mechanisms and long-term safety.
