Effects of HMGB1 on phenotypes, phagocytosis and ERK/JNK/P38 MAPK signaling pathway in dendritic cells
- Author:
Ying-Ying CHEN
1
;
Zhi-Xiang MOU
1
;
Xiao-Long HU
1
;
Yi-Yan ZHANG
1
;
Jiao-Qing WENG
1
;
Tian-Jun GUAN
1
;
Ying-Ying CHEN
2
;
Lan CHEN
2
;
Tian-Jun GUAN
2
;
Lan CHEN
3
;
Pei-Yu LYU
4
Author Information
- Publication Type:Journal Article
- Keywords: dendritic cells; HMGB 1; indoxyl sulfate; phagocytosis; phenotype
- From: Chinese Pharmacological Bulletin 2024;40(2):248-255
- CountryChina
- Language:Chinese
- Abstract: Aim To explore the impacts of high mobility group box 1 (HMGB1) on the phenotypes, endocy-tosis and extracellular signal-regulated kinase (ERK)/ Jun N-terminal protein kinase (JNK)/P38 mitogen-ac-tivated protein kinase (MAPK) signaling pathway in indoxyl sulfate (IS) -induced dendritic cells (DCs). Methods After treatment with 30, 300 and 600 (xmol · L
