Choriocarcinoma presenting as late postpartum hemorrhage in a 21-year-old primipara
- Author:
Shelyne Rose Soriano Cruz
1
;
Elizabeth Karunungan Jacinto
1
Author Information
- Publication Type:Case Reports
- MeSH: Choriocarcinoma; Gestational Trophoblastic Disease; Postpartum Hemorrhage
- From: Philippine Journal of Obstetrics and Gynecology 2024;48(1):72-76
- CountryPhilippines
- Language:English
-
Abstract:
Introduction:Obstetrical hemorrhage remains to be one of the most common causes of maternal morbidity and mortality. Postpartum hemorrhage occurs after delivery and is usually secondary to uterine atony, genital tract lacerations, and retained placental fragments.
Case:A case of a 21-year old, primipara, presented with profuse vaginal bleeding and hemoptysis at 3 weeks' postpartum. A clinical diagnosis of gestational trophoblastic neoplasia was established after an elevated serum beta human chorionic gonadotropin was obtained and an intrauterine mass was seen on ultrasonography, including metastasis to the lungs and liver seen through imaging studies.
Discussion:Chemotherapy with etoposide, methotrexate, actinomycin D, cyclophosphamide and oncovin (EMACO) is the mainstay treatment for Stage IV disease. However, complications such as hemorrhage and tumor rupture are best managed surgically. Although rare, a diagnosis of choriocarcinoma should be considered in patients with persistent bleeding after a normal pregnancy to institute proper management and avoid associated complications of tumor progression. - Full text:choriocarcinoma_presenting_as_late_postpartum.9.pdf
