Current status of research on the genetic susceptibility of primary biliary cholangitis
- VernacularTitle:原发性胆汁性胆管炎遗传易感性的研究现状
- Author:
Chunmei ZHAO
1
;
Di MA
1
;
Wenlin TAI
1
Author Information
- Publication Type:Review
- Keywords: Primary Biliary Cholangitis; Genetic Predisposition to Disease; HLA Antigens
- From: Journal of Clinical Hepatology 2024;40(3):606-610
- CountryChina
- Language:Chinese
- Abstract: Primary biliary cholangitis （PBC） is a liver autoimmune disease with a strong genetic tendency characterized by the degeneration and necrosis of bile duct epithelial cells， and it is often observed in middle-aged and elderly women. With the continuous development of genome-wide association studies， the genetic susceptibility of PBC has attracted more and more attention. This article elaborates on the research advances in the genetic susceptibility genes closely associated with PBC， in order to provide effective targets for the treatment of PBC.
