Research progress on the regulation of intestinal flora and effect on intestinal absorption and transport by TCM components
10.12206/j.issn.2097-2024.202303012
- VernacularTitle:中药成分调控肠道菌群影响肠吸收转运的研究进展
- Author:
Jun JIANG
1
;
Li CHEN
1
;
Zhong LI
1
;
Jin’ge LIU
1
;
Tian QI
1
;
Tingting ZHOU
2
Author Information
1. School of Basic Medicine, Naval Medical University, Shanghai 200433, China.
2. Shanghai Key Laboratory for Pharmaceutical （Chinese Materia Medica） Metabolite Research, Shanghai 200433, China.
- Keywords:
intestinal microbiota;
Traditional Chinese Medicine ingredients;
intestinal barrier;
absorption transport
- From:
Journal of Pharmaceutical Practice and Service
2024;42(3):89-93
- CountryChina
- Language:Chinese
-
Abstract:
The domestic and international research progress on the regulation of gut microbiota by Traditional Chinese Medicine (TCM) ingredients and their impact on intestinal absorption and transportation were summarized, which provided assistance for subsequent clinical rational drug use targeting gut microbiota. Literature on the relationship between gut microbiota and intestinal absorption and transportation in recent years were reviewed and analyzed, and the mechanism of TCM ingredients regulating gut microbiota on drug absorption and transportation was elucidated. Research has found that TCM ingredients alter gut microbiota, thereby affecting intestinal barrier function and absorption of transport proteins, which is of great significance for rational clinical medication.
