Progress of research on the preventive and therapeutic agents against radiation-induced injuries
10.13491/j.issn.1004-714X.2024.01.019
- VernacularTitle:放射性损伤相关防治药物研究进展
- Author:
Junfeng XUE
1
;
Shu SUN
1
;
Yunyun JIANG
1
;
Weili QI
1
;
Wei HU
1
Author Information
1. Department of Pharmacy, 904 Hospital of PLA, Wuxi 214044 China.
- Publication Type:ReviewArticles
- Keywords:
Radiation-induced injury;
Radiation protection;
Radiation exposure
- From:
Chinese Journal of Radiological Health
2024;33(1):106-110
- CountryChina
- Language:Chinese
-
Abstract:
Radiation-induced injury, a body dysfunction caused by irradiation, is associated with the dose, duration, and speed of radiation and is predominantly derived from radiation therapy for patients with malignant tumors. The current clinical treatment mainly includes amelioration of injury, alleviation of symptoms, and improvements in function restoration of the affected sites because of lack of targeted agents specific to radiation-induced injuries. Research and development of preventive and therapeutic agents against radiation-induced injuries are of great significance to reduce the body damages caused by radiotherapy and improve the quality of life of cancer survivors. This review summarizes the radiation-induced injury and its mechanisms, radioprotectants, and therapeutic agents for radiation, and proposes future development directions, so as to provide a reference for alleviation of radiation-induced injury and improvement in prognosis.
