Concurrent hepatic adenomatoid tumor and hepatic hemangioma: a case report.
10.3350/cmh.2012.18.2.229
- Author:
Ji Beom KIM
1
;
Eunsil YU
;
Ju Hyun SHIM
;
Gi Won SONG
;
Gwang Un KIM
;
Young Joo JIN
;
Ho Seop PARK
Author Information
1. Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
- Publication Type:Case Reports
- Keywords:
Adenomatoid tumor;
Liver;
Hemangioma
- MeSH:
Adenomatoid Tumor/*diagnosis/pathology/surgery;
Calcium-Binding Protein, Vitamin D-Dependent/metabolism;
Hemangioma/*diagnosis/pathology/surgery;
Hepatectomy;
Humans;
Keratins/metabolism;
Liver Neoplasms/*diagnosis/pathology/surgery;
Magnetic Resonance Imaging;
Male;
Middle Aged;
Neprilysin/metabolism;
Tomography, X-Ray Computed;
Vimentin/metabolism
- From:Clinical and Molecular Hepatology
2012;18(2):229-234
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 45-year-old male with alleged asymptomatic hepatic hemangioma of 4 years duration had right upper-quadrant pain and was referred to a tertiary hospital. Computed tomography and magnetic resonance imaging scans revealed a hypervascular mass of about 7 cm containing intratumoral multilobulated cysts. A preoperative liver biopsy was performed, but this failed to provide a definitive diagnosis. The patient underwent a partial hepatectomy of segments IV and VIII. The histologic findings revealed multifocal proliferation of flattened or cuboidal epithelioid cells and a highly vascular edematous stroma. Immunohistochemistry findings demonstrated that the epithelioid tumor cells were positive for cytokeratin (AE1/AE3), vimentin, calretinin, and cytokeratin 5/6, and were focally positive for CD10, and negative for WT1 and CD34, all of which support their mesothelial origin. Immunohistochemistry for a mesothelial marker should be performed for determining the presence of an adenomatoid tumor when benign epithelioid cells are seen.
