Association between the ratio of dietary vitamin A to body weight and hypertension in children
10.16835/j.cnki.1000-9817.2024062
- VernacularTitle:膳食维生素A和体重的比值与儿童高血压的相关性
- Author:
CHENG Ping, REN Yanling, LIU Qin, CHEN Lanling, TONG Jishuang, XIAO Lun,QIN Jun, LI Xinggui, MA Jun, XU Lin, SHI Xiuzhen, WANG Li, WAN Lingjuan, LIANG Xiaohua
1
Author Information
1. Department of Pharmacy, People s Hospital of Shimian County, Yaan (625499) , Sichuan Province, China
- Publication Type:Journal Article
- Keywords:
Diet;
Vitamin A;
Body weight;
Hypertension;
Regression analysis;
Child
- From:
Chinese Journal of School Health
2024;45(2):267-272
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the relationship between the ratio of dietary vitamin A (VitA) to body weight and hypertension among children, so as to provide a reference for blood pressure control through dietary nutritional interventions and childhood hypertension prevention.
Methods:Utilizing the baseline survey and followup sample data from the Healthy Children Cohort established in urban and rural areas of Chongqing from 2014 to 2019, structured quantitative dietary questionnaire and selfdesigned questionnaire were used to investigate the information of dietary intake and socioeconomic characteristics of 15 279 children, as well as blood pressure, height, weight measurement. The ratio of dietary VitA to body weight was divided into four groups based on quartiles [≤P25(Q1), >P25~P50(Q2), >P50~P75(Q3), >P75(Q4)]. Generalized linear regression models and Logistic regression models were used to analyze the correlation between ratio of dietary VitA to body weight with blood pressure levels and prevalence of hypertension.
Results:The results of the 2014 baseline survey indicated that, after adjusting for confounding factors such as demographic indicators and nutritional intake, significant differences were observed in systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) among different groups categorized by the ratio of dietary VitA to body weight (F=157.57, 44.71, 95.92, P<0.01). The baseline ratio of dietary VitA to body weight in children exhibited a negative correlation with DBP, SBP and MAP at baseline and in 2019[baseline: β(95%CI)=-0.65(-0.89--0.42), -0.22(-0.42--0.01), -0.36(-0.56--0.16); 2019: β(95%CI)=-0.77(-1.34--0.19), -0.62(-1.21--0.02), -0.77(-1.34--0.19), P＜0.05]. Compared to Q1 group, the risk of hypertension decreased among children in Q4 at baseline and followup in 2019 [OR(95%CI)=0.63(0.49-0.81), 0.18(0.08-0.42), P<0.01].
Conclusions:The ratio of dietary VitA to body weight is significantly negatively correlated with blood pressure levels among children, and dietary VitA deficiency is an independent risk factor for hypertension among children. Measures should be taken to actively adjust childrens dietary nutrition and reduce the risk of childhood hypertension.
