Predictors for hemorrhagic transformation among patients with Ischemic stroke admitted in a Tertiary Hospital in the Philippines from July 2018-July 2019
https://doi.org/10.47895/amp.vi0.6748
- Author:
Sofia Maria S. Im
1
;
Ma. Teresa A. Cañete
1
Author Information
1. Section of Neurology, Department of Internal Medicine, Chong Hua Hospital, Cebu City, Philippines
- Publication Type:Journal Article
- Keywords:
Hemorrhagic transformation;
Predictors
- MeSH:
Ischemic Stroke;
Philippines
- From:
Acta Medica Philippina
2024;58(3):40-46
- CountryPhilippines
- Language:English
-
Abstract:
Background:Among the multiple scoring systems for hemorrhagic transformation, only few of these address spontaneous hemorrhagic transformation after an ischemic stroke, with most done with Western population data.
Objectives:This study aims to identify the predictors for hemorrhagic transformation among patients with ischemic stroke admitted in a tertiary hospital in Cebu City, Philippines.
Methods:This is a retrospective cohort study of patients with ischemic stroke admitted in a tertiary hospital in
Cebu City. Patients’ baseline characteristics, clinical, and radiologic data were collected. Chi square test and t-test were used to determine which variables were significantly different between patients with and without hemorrhagic transformation. Odds ratio (OR) and 95% confidence interval (CI) were determined to measure the association between the different variables and hemorrhagic transformation.
Results:A total of 500 ischemic stroke patients were included in the study. There were 28 (6%) ischemic stroke
patients with Hemorrhagic Transformation. The mean age of these patients is 66.93 ± 12.42 years, 48.8% male, 10.8% had atrial fibrillation, and 2.4% had myocardial infarction. Controlling for the effect of confounders, white blood cell count (OR 1.11; 95% CI 1.03-1.19), myocardial infarction (OR 5.25; 95% CI 1.13-24.34), and presence of brain edema (OR 2.86; 95% CI 1.05-7.80) were significant predictors of hemorrhagic transformation.
Conclusion:White blood cell count, presence of brain edema, and myocardial infarction were significantly associated with hemorrhagic transformation among ischemic stroke patients.
- Full text:6748-Article Text-99007-2-10-20240227.pdf
