Lymphomatoid gastropathy: one case report and literatures review.
10.3760/cma.j.issn.0253-2727.2018.11.013
- Author:
Yang Zhong ZHOU
1
;
Yan ZHANG
;
Wei Yang ZHEN
;
Sheng Yu ZHANG
;
Jian SUN
;
Zhao Hui LU
;
Wei ZHANG
;
Dao Bin ZHOU
;
Tie Nan ZHU
Author Information
1. Department of Internal Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinsese Academy of Medical Sciences, Beijing 100730, China.
- Publication Type:Review
- Keywords:
EBER;
Gut;
Lymphomatoid gastropathy;
NK/T-cell lymphoma
- MeSH:
Biopsy;
China;
Female;
Humans;
Immunophenotyping;
In Situ Hybridization;
Lymphatic Diseases;
Lymphoma, T-Cell, Peripheral;
Middle Aged;
Stomach Diseases
- From:
Chinese Journal of Hematology
2018;39(11):937-941
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To report the first case of lymphomatoid gastropathy in China, and to demonstrate the clinical characteristics, diagnostic approach, treatment and prognosis in this kind of patients. Methods: One patient was diagnosed as lymphomatoid gastropathy at Peking Union Medical College Hospital, and her clinical characteristics, lab data, treatment and follow-up outcomes were reviewed. Results: A case of a 51-year-old female was presented, who underwent esophagogastroduodenoscopy (EGD) due to slight epigastric discomfort. EGD revealed multiple ulcers and erosions. Biopsies showed atypical lymphocytes infiltration with CD3(+), CD56(+), CD20(-), CD8(-), TIA(+), Granzyme B(-) and Ki-67 (75%). Epstein-Barr virus-encoded RNA in situ hybridization was negative. Four months later, repeated EGD examination showed regression of the lesions without specific treatment. Conclusion: Lymphomatoid gastropathy was a unique disease entity mimicking NK/T-cell lymphomas in pathology, with the quite different profile of treatment and prognosis. It's important to consider this issue during the differential diagnosis to avoid any excessive treatment.
