The diagnostic value of PLASMIC score in the discrimination between thrombotic thrombocytopenic purpura and disseminated intravascular coagulation.
10.3760/cma.j.issn.0253-2727.2018.10.005
- Author:
Jie YIN
1
;
Zi Qiang YU
;
Dan Qing KONG
;
Zhao Yue WANG
;
Jun JIN
;
Jun WANG
;
Xue Ming WANG
;
Jian SU
;
Wei ZHANG
;
Chang Geng RUAN
Author Information
1. Jiangsu Institute of Hematology, MOH Key Lab of Thrombosis and Hemostasis, The First Affiliated Hospital of Soochow University, Collaborative Innovation Center of Hematology, Soochow University, Suzhou 215006, China.
- Publication Type:Journal Article
- Keywords:
Diagnosis;
Disseminated intravascular coagulation;
PLASMIC score;
Thrombotic thrombocytopenic pupura
- MeSH:
Blood Coagulation Tests;
Disseminated Intravascular Coagulation;
Humans;
Platelet Count;
Purpura, Thrombotic Thrombocytopenic;
Retrospective Studies
- From:
Chinese Journal of Hematology
2018;39(10):812-816
- CountryChina
- Language:Chinese
-
Abstract:
Objective: PLASMIC score was evaluated its value in differential diagnosis between the patients with thrombotic thrombocytopenic purpura (TTP) and those with disseminated intravascular coagulation (DIC) . Method: Twenty-four patients with TTP and 41 cases with DIC were retrospectively analyzed in this study. The platelet count, average red blood cell volume, indirect bilirubin, creatinine and prothrombin time international normalised ratio were collected, and then PLASMIC scores were calculated. Results: According to the risk classification of PLASMIC score, three (12.5%) TTP patients had moderate risk, and the rest 21 (87.5%) cases had high risk. In DIC patients, 92.7% cases were in low risk group, 4.9% at moderate risk, and only one case had high risk. Of these 65 patients, the sensitivity and the specificity to TTP of the high risk of the scoring system were 87.5% and 97.6%, respectively. Conclusion: The patients with high risk of PLASMIC score correlated well with clinical TTP diagnosis. The scoring system showed to be an excellent diagnostic model to distinguish TTP patients from those with DIC.
