Chest CT Imaging Features of Indeterminate Pulmonary Nodules and Outcomes in Patients with High-grade Soft Tissue Sarcoma: A Single-center Retrospective Study
10.3971/j.issn.1000-8578.2024.23.0810
- VernacularTitle:高级别肉瘤患者肺部不确定性质结节胸部CT影像学特征与转归：一项单中心回顾性研究
- Author:
Yuanrong WANG
1
;
Liming ZHANG
;
Daji SONAM
;
Yan ZHU
;
Gentao FAN
;
Yicun WANG
;
Xin SHI
;
Sujia WU
;
Guangxin ZHOU
Author Information
1. Department of Orthopaedics, Eastern Theater General Hospital of PLA (Jinling Hospital, Medical School of Nanjing University), Nanjing 210018, China
- Publication Type:Research Article
- Keywords:
High-grade soft tissue sarcoma;
Pulmonary nodules;
Computer tomography;
Prognosis
- From:
Cancer Research on Prevention and Treatment
2024;51(2):99-103
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the imaging features, clinical outcome, and prognosis of indeterminate pulmonary nodules (IPN) in patients with high-grade soft tissue sarcoma. Methods A retrospective study of 82 patients with high-grade soft tissue sarcoma who have IPNs. The clinical characteristics, imaging features of IPN, and survival of patients were analyzed with statistical software. Results The IPN size of 82 patients was 6.453±0.864 mm. IPN diameter, shape, density, and nodule discovery interval may be CT imaging features related to malignancy tendency. Age (HR=1.047, 95%CI: 1.007-1.088) and interval between each nodule discovery (HR=3.194, 95%CI: 1.052-9.694) are independent factors that affect the survival of patients with malignant IPN. Conclusion The imaging features of chest CT may provide important guidance for determining the nature and survival prognosis of benign and malignant nodules.
