Antimicrobial Activities of Mangrove Species in Southeast Asia: A Systematic Review (Aktiviti Antimikrob Spesies Bakau di Asia Tenggara: Tinjauan Sistematik)
http://dx.doi.org/10.17576/JSKM-2023-2102-08
- Author:
MA. MELANIE DALAINE DELA CRUZ CARNAJE
1
;
JON DAVE TORRES REBENQUE
1
;
GARY ANTONIO CENIDOZA LIRIO
2
Author Information
1. Department of Biology, Polytechnic University of the Philippines
2. Research Institute for Science and Technology, Center for Natural Sciences and Resources Research, Polytechnic University of the Philippines
- Publication Type:Journal Article
- Keywords:
Mangroves;
antimicrobial activities;
Southeast Asia;
antimicrobial resistance;
Systematic review
- From:Malaysian Journal of Health Sciences
2023;21(No.2):85-105
- CountryMalaysia
- Language:English
-
Abstract:
Antimicrobial resistance in Southeast Asia is a macro-level health dilemma that may cause substantial casualties
annually. Fortunately, Southeast Asian mangroves are potent reservoirs of bioactive compounds with antimicrobial
properties in correlation to their traditional usage. Hence, this study aimed to systematically review studies concerning
antimicrobial activities of mangroves in Southeast Asia as well as provide a technological overview of its prospective
use in pharmaceutical industry applications through patents. Through the PRISMA protocol, the search for peerreviewed studies originated from Southeast Asia and published between 2010 to 2022 were conducted over databases
such as CORE, Google Scholar, PubMed (MedLine), Science Direct, Semantic Scholar, Scopus, and Web of Science.
Additionally, a patent search was also performed on the Espacenet Patent Search, Google Patents, National Institute of
Industrial Property, and United States Patent and Trademark Office. The studies and patents were collated on Mendeley
Reference Manager as well as tabulated and assessed on Microsoft Office Excel 2016. After the four-phase screening,
59 studies and one patent regarding antimicrobial activities of Southeast Asian mangroves passed the criteria for the
systematic review. It was inferred that Southeast Asia constitutes potentially most species-diverse mangroves with highly
varied antimicrobial properties and can form synergism with drugs. The existing studies and patents may provide
enlightenment on the future path of studies and inventions which must be continually substantiated in animal and
clinical experiments for prospective pharmaceutical industry use. In this way, mangroves can be conserved while
antimicrobial resistance and anthropogenic activities can be lowered.
- Full text:14.2023my0447.pdf
