Investigations of clinical characteristics and inflammatory markers of febrile seizures induced by coronavirus infection
https://doi.org/10.47665/tb.40.4.009
- Author:
Zhao, L.
1
;
Wu, H.Y.
1
;
Xie, D.
1
;
Mo, L.M.
1
;
Yang, F.F.
1
;
Gao, Y.
1
;
Zhao, X.L.
1
;
He, Y.Z.
2
Author Information
1. Department of Pediatric intensive care unit, Sanya Women and Childrens Hospital/AffIliated to Shanghai Jiao Tong University School of Medicine Shanghai Childrens Medical Center Hainan Branch, Sanya 572000, China
2. Department of Neurology, Shanghai Childrens Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
- Publication Type:Journal Article
- Keywords:
COVID-19;
febrile seizure;
convulsion duration;
drug prevention;
inflammatory factors.
- From:Tropical Biomedicine
2023;40(No.4):439-443
- CountryMalaysia
- Language:English
-
Abstract:
The study of children who experienced with febrile seizures(FS) as a result of COVID-19 infection to gain
insight into the clinical characteristics and prognosis of neurological damage, with the aim of improving
prevention, diagnosis, and the treatment of neurological complications. This study investigated the
clinical features of 53 children with FS who were admitted to Sanya Women and Children’s Hospital
from December 1, 2022, to January 31, 2023. The results indicated that the duration of convulsion in
the case and control group was 7.90±8.91 and 2.67±1.23 (minutes) respectively. The analysis reveals
that convulsions occurred within 24 hours in 39 cases (95.12%) of the case group, and in 8 cases
(66.7%) of the control group. The difference was statistically significant (P<0.05). Additionally, the case
group presented lower counts of WBC and NEU compared to the control group (p<0.05). The findings
indicate that convulsions manifest at earlier stages of COVID-19 in children and the last longer than
in the control group. It is therefore crucial for healthcare workers to remain attentive to patients with
COVID-19 who report fever within 24 hours, and act promptly to implement preventive measures,
particularly in cases of prolonged fever. It is essential to integrate the clinical manifestation, particularly
convulsions, and the continuous numerical changes of inflammatory factors to assess COVID-19 linked
with febrile seizures. In addition, larger-scale multi-center and systematic research are necessary to
aid clinicians in monitoring neuropathological signals and biological targets, enabling more equitable
diagnosis and treatment plans.
- Full text:8.2023my1440.pdf
