Discovery of a potent and selective cell division cycle 7 inhibitor from 6-(3-fluoropyridin-4-yl)thieno3,2-<i>d</i>pyrimidin-4(3<i>H</i>)-one derivatives as an orally active antitumor agent.

Author: Mingwei FU ¹ ; Min GE ² ; Wanxiang YANG ¹ ; Chunchen HU ² ; Xiaowei LI ² ; Yuanjiang WANG ¹ ; Shaohua GOU ¹
Author Information

1. Pharmaceutical Research Center and School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.
2. Zenji Research Laboratories, Nanjing 211189, China.
Publication Type:Journal Article
Keywords: Anti-tumor; CDC7 inhibitor; Cell division cycle 7; DNA replication
From: Acta Pharmaceutica Sinica B 2024;14(2):893-896
CountryChina
Language:English