A Case of Cytomegalovirus Pneumonia and Retinitis in a Patients with Systemic Lupus Erythematosus.
- Author:
Seung Ho HAN
1
;
You Jeong SOHN
;
Min A PARK
;
Sang LEE
;
Seung Hoon RYU
;
Tae Hyung LIM
;
Dong Sung JUNG
;
Young Ki SON
;
Mee Sook ROH
;
Mi Kyung PARK
;
Sung Won LEE
;
Won Tae CHUNG
Author Information
1. Department of Internal Medicine, Dong-A University Hospital, Busan, Korea. comeinus@damc.or.kr
- Publication Type:Case Report
- Keywords:
SLE;
CMV infection;
Pneumonia;
CMV retinitis
- MeSH:
Acquired Immunodeficiency Syndrome;
Bone Marrow Transplantation;
Cyclophosphamide;
Cytomegalovirus*;
DNA Viruses;
Ganciclovir;
Herpesviridae;
Humans;
Immunoglobulins;
Korea;
Lung Diseases, Interstitial;
Lupus Erythematosus, Systemic*;
Mortality;
Organ Transplantation;
Pneumonia*;
Prednisolone;
Retinitis*;
Transplants
- From:The Journal of the Korean Rheumatism Association
2003;10(4):456-461
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cytomegalovirus (CMV) is the member of the herpesviridae of virus, which are large DNA viruses that share the biologic properties of latency and reactivation. In patients with advanced acquired immune deficiency syndrome (AIDS) and those immunocompomised due to bone marrow transplantation or solid organ transplantation, CMV infection is the major cause of morbidity and mortality. CMV pneumonia is the most severe complication of these CMV disease. There have been reported a few cases of CMV interstitial pneumonitis occurring in a patient with SLE after intensive immunosuppressive therapy with prednisolone and cyclophosphamide, and there has been reported a case in Korea. Then we report a case of CMV pneumonia and retinitis occurring in a patient with SLE who was being treated with high dose steroid for 1 month, and was treated with ganciclovir and immunoglobulin.