A case of sudden hearing loss combined with familial hyperlipidemia.
10.13201/j.issn.20967993.2024.01.011
- Author:
Hui ZHONG
1
;
Xiaonan WU
2
;
Jing GUAN
2
;
Dayong WANG
2
;
Qiuju WANG
2
Author Information
1. Southern Medical University，Guangzhou，510515，China.
2. Senior Department of Otolaryngology-Head & Neck Surgery，the Sixth Medical Center of PLA General Hospital.
- Publication Type:Journal Article
- Keywords:
hyperlipemia;
lipid metabolism;
sudden hearing loss
- MeSH:
Humans;
Audiometry, Pure-Tone;
Deafness/complications*;
Hearing Loss, Sensorineural/diagnosis*;
Hearing Loss, Sudden/diagnosis*;
Hyperlipidemias/complications*;
Lipids
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2024;38(1):70-72
- CountryChina
- Language:Chinese
-
Abstract:
Hyperlipidemia is characterized by elevated levels of blood lipids. The clinical manifestations are mainly atherosclerosis caused by the deposition of lipids in the vascular endothelium. The link between abnormal lipid metabolism and sudden hearing loss remains unclear. This article presents a case study of sudden hearing loss accompanied by familial hyperlipidemia. Pure tone audiometry indicated intermediate frequency hearing loss in one ear. Laboratory tests showed abnormal lipid metabolism, and genetic examination identified a heterozygous mutation in theAPOA5 gene. Diagnosis: Sudden hearing loss; hypercholesterolemia. The patient responded well to pharmacological treatment. This paper aims to analyze and discuss thepotential connection between abnormal lipid metabolism and sudden hearing loss.
