Research progress on hereditary endocrine and metabolic diseases associated with sensorineural hearing loss.
10.13201/j.issn.2096-7993.2024.01.010
- Author:
Fang CHEN
1
;
Qinying ZHANG
1
;
Qiujing ZHANG
2
;
Qiuju WANG
2
Author Information
1. Traditional Chinese Medicine Endocrinology Department of the 985th Hospital of the Joint Logistics Support Force of the People's Liberation Army，Taiyuan，030001，China.
2. Department of Audiology and Vestibular Medicine，Institute of Otolaryngology，Senior Department of Otolaryngology Head and Neck Surgery，the First Medical Center of Chinese PLA General Hospital，National Clinical Research Center for Otolaryngologic Diseases.
- Publication Type:Journal Article
- Keywords:
endocrinology disease;
gene;
hearing impairment;
inherited metabolic disease
- MeSH:
Humans;
Deafness/genetics*;
Hearing Loss, Sensorineural/diagnosis*;
Phenotype;
Metabolic Diseases/genetics*;
Genetic Counseling
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2024;38(1):63-69
- CountryChina
- Language:Chinese
-
Abstract:
Hereditary endocrine and metabolic diseases , caused by genetic factors, exhibit complex and diverse symptoms, including the possibility of concurrent sensorineural deafness. Currently, there is a limited clinical understanding of hereditary endocrine and metabolic diseases that manifest with deafness, the pathogenesis remains unclear,and there is a lack of effective diagnostic and treatment methods. This article summarizes the research progress of hereditary endocrine and metabolic diseases complicated with deafness from the pathogenesis, clinical phenotype, diagnosis and treatment. Understanding the current research progress and integrating genetic analysis into clinical practice are crucial for accurate diagnosis and treatment, evaluating clinical efficacy, and providing effective genetic counseling for these diseases.
