Clinical analysis of 5 adult laryngeal rhabdomyosarcoma.
10.13201/j.issn.2096-7993.2023.12.018
- Author:
Yuanyuan SHEN
1
;
Liuzhong WANG
2
;
Hua CAO
2
Author Information
1. Department of Otolaryngology，Xuchang Central Hospital，Xuchang，461000，China.
2. Department of Pharyngology Head and Neck Surgery，the First Affiliated Hospital of Zhengzhou University.
- Publication Type:Journal Article
- Keywords:
laryngeal neoplasms;
prognosis;
rhabdomyosarcoma;
treatment
- MeSH:
Adult;
Humans;
Retrospective Studies;
Neoplasm Recurrence, Local/therapy*;
Larynx/pathology*;
Rhabdomyosarcoma/therapy*;
Vocal Cords/pathology*
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2023;37(12):1014-1018
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical manifestations,the type of pathology, treatment and prognosis of laryngeal rhabdomyosarcoma, and to enhance the understanding of the clinical characteristics of the disease, while improving the diagnosis rateand reducing the misdiagnosis rate, in order to explore effective diagnosis and treatment methods. Methods:A retrospective analysis was conducted on the clinical data of 5 cases of laryngeal rhabdomyosarcoma treated in the First Affiliated Hospital of Zhengzhou University from May 2015 to May 2021. Results:All 5 cases of laryngeal rhabdomyosarcoma were misdiagnosed in the early stage. with tumors mostly occurring in the vocal cords and appearing as smooth mass. The clinical symptoms were mostly hoarseness. According to pathological classification, three cases were embryonic type, one case was polymorphic type, and one case was spindle type.Three patients died due to tumor recurrence, one patient had multiple systemic metastases, and another patient who underwent surgical resection in the early stage and supplemented with postoperative radiotherapy and chemotherapyhas been followed up to date without recurrence. Conclusion:Laryngeal rhabdomyosarcoma has low incidence rate, high malignancy degree and poor prognosis. It is easy to be misdiagnosed as a benign mass. Extensive surgical resection combined with radiotherapy and chemotherapy should be performed as soon as possible after diagnosis.
