Diffuse large B-cell lymphoma of thyroid invading the superior mediastinum with hashimoto's thyroiditis: a case report and literature review.
10.13201/j.issn.2096-7993.2023.09.012
- Author:
Jiamu LV
1
;
Tingting YU
1
;
Wanzhong YIN
1
Author Information
1. Department of Otolaryngology Head and Neck Surgery，the First Hospital of Jilin University，Changchun，130021，China.
- Publication Type:Journal Article
- Keywords:
diffuse large B-cell lymphoma;
lymphomas;
primary thyroid lymphoma;
thyroid malignancies
- MeSH:
Humans;
Mediastinum;
Retrospective Studies;
Hashimoto Disease;
Lymphoma, Large B-Cell, Diffuse;
Thyroid Neoplasms
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2023;37(9):755-758
- CountryChina
- Language:Chinese
-
Abstract:
This article reports a case of primary thyroid diffuse large B-cell lymphoma involving the superior mediastinum with Hashimoto's thyroiditis admitted to the Department of Otolaryngology and Head and Neck Surgery, First Hospital of Jilin University. This patient underwent right thyroid lobectomy and was transferred to the Department of Hematology of the Oncology Center for 6 courses of chemotherapy with R-CHOP protocol. The postoperative recovery was good, and the patient was regularly followed up for 12 months after the operation. The patient's condition was stable, and CT showed no abnormally high metabolism in the operation area indicating the inhibition of tumor activity, superficial lymph nodes and peripheral blood cells were normal. The case encountered many difficulties in the diagnosis process, and the diagnosis was not confirmed after puncture in two Grade III Class A hospitals in China. There are few patients with primary thyroid diffuse large B-cell lymphoma complicated with Hashimoto's thyroiditis, and it is particularly rare to invade the mediastinum. There is no report in China and abroad in the literature we reviewed. Therefore, this article reports the case and retrospectively analyzes the etiology, clinical symptoms, diagnosis and treatment of primary thyroid lymphoma.
