Two children with late-onset congenital central hypoventilation syndrome.
10.13201/j.issn.2096-7993.2023.08.011
- Author:
Shuyao QIU
1
;
Liqiang YANG
1
;
Jianwen ZHONG
1
;
Xiangqian LUO
1
;
Dabo LIU
1
Author Information
1. Pediatric Otolaryngology Department of Shenzhen Hospital，Southern Medical University，Shenzhen，518000，China.
- Publication Type:Journal Article
- Keywords:
central hypoventilation;
children;
congenital;
non-invasive ventilation
- MeSH:
Humans;
Child;
Male;
Female;
Infant;
Sleep Apnea, Central/therapy*;
Respiration, Artificial;
Hypoventilation/congenital*;
Oxygen
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2023;37(8):656-666
- CountryChina
- Language:Chinese
-
Abstract:
Two children with late-onset congenital central hypoventilation syndrome were reported, one of whom was male and had no abnormal manifestations after birth, respiratory failure occurs at the age of 1 year and 6 months. After being hospitalized, he was treated with oxygen inhalation and non-invasive ventilation, but carbon dioxide retention could not be corrected. After one month of tracheal intubation, he was failure to wean from ventilator, so tracheostomy was performed. He needs a ventilator to help breath while sleeping, and can breath autonomously during the day without ventilator. The other case was a female, with no abnormalities after birth. At the age of 11 months, she developed respiratory failure. During sleep, the child needs non-invasive assisted ventilation through a nasal mask, and during the day, she breathed autonomously.Two patients were followed up forever 2 years and their growth and development were normal.
