Research advances on neurally adjusted ventilatory assist.
10.3760/cma.j.cn121430-20230222-00101
- Author:
Yuliang SHENG
1
;
Wei SHAO
2
;
Yuhao WANG
1
;
Xiuwen KANG
3
;
Rong HU
1
Author Information
1. Department of Respiratory and Critical Care Medicine, the Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang 222000, Jiangsu, China.
2. Jinzhou Medical University, Jinzhou 121000, Liaoning, China.
3. Department of Critical Care Medicine, the Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang 222000, Jiangsu, China. Corresponding author: Hu Rong, Email: huronglygyy2018@163.com.
- Publication Type:Journal Article
- MeSH:
Humans;
Interactive Ventilatory Support;
Respiration, Artificial;
Positive-Pressure Respiration;
Diaphragm/physiology*;
Respiratory Muscles/physiology*
- From:
Chinese Critical Care Medicine
2023;35(11):1229-1232
- CountryChina
- Language:Chinese
-
Abstract:
Mechanical ventilation has, since its introduction into clinical practice, undergone a major evolution from controlled ventilation to diverse modes of assisted ventilation. Conventional mechanical ventilators depend on flow sensors and pneumatic pressure and controllers to complete the respiratory cycle. Neurally adjusted ventilatory assist (NAVA) is a new form of assisted ventilation in recent years, which monitors the electrical activity of the diaphragm (EAdi) to provide an appropriately level of pressure support. And EAdi is the best available signal to sense central respiratory drive and trigger ventilatory assist. Unlike other ventilation modes, NAVA breathing instructions come from the center. Therefore, NAVA have the synchronous nature of the breaths and the patient-adjusted nature of the support. Compared with traditional ventilation mode, NAVA can efficiently unload respiratory muscles, relieve the risk of ventilator-induced lung injury (VILI), improve patient-ventilator coordination, enhance gas exchange, increase the success rate of weaning, etc. This article reviews the research progress of NAVA in order to provide theoretical guidance for clinical applications.
