Progress in pharmaceutical research for cerebral resuscitation after cardiac arrest.
10.3760/cma.j.issn.2095-4352.2019.03.023
- Author:
Song XU
1
;
Liping LU
;
Yingtao LIAN
;
Zhui YU
Author Information
1. Department of Critical Care Medicine, People's Hospital of Wuhan University, Wuhan 430060, Hubei, China. Corresponding author: Yu Zhui, Email: yuzhui@whu.edu.cn.
- Publication Type:Review
- MeSH:
Cerebrovascular Circulation/drug effects*;
Heart Arrest/drug therapy*;
Humans;
Pharmaceutical Research/trends*;
Resuscitation/methods*
- From:
Chinese Critical Care Medicine
2019;31(3):371-374
- CountryChina
- Language:Chinese
-
Abstract:
With the popularization of cardiopulmonary resuscitation (CPR) technology, the success rate of restoration of spontaneous circulation (ROSC) is gradually improved, and the survival rate and neurological outcome of patients with cardiac arrest are improved. Currently, therapeutic methods for cerebral resuscitation after cardiac arrest are limited. In addition to mild hypothermia for clinical application, the majority of drugs remain in the animal experimental stage. Finding effective brain protection drugs has become a hot spot in the field of brain resuscitation research. This article will review the pharmaceutical progress of research for cerebral resuscitation after cardiac arrest, so that we can study the brain protection mechanism of these drugs better and more targeted.
