- Author:
Sun Wook CHO
1
Author Information
- Publication Type:Review
- Keywords: Osteal macrophage; Bone remodeling; Fracture healing
- MeSH: Bone Development; Bone Marrow; Bone Remodeling; Fracture Healing; Macrophages*; Metabolism*
- From:Journal of Pathology and Translational Medicine 2015;49(2):102-104
- CountryRepublic of Korea
- Language:English
- Abstract: Macrophages have been shown to have pleiotropic functions in various pathophysiologies, especially in terms of anti-inflammatory and regenerative activity. Recently, the novel functions of bone marrow resident macrophages (called osteal macrophages) were intensively studied in bone development, remodeling and tissue repair processes. This review discusses the current evidence for a role of osteal macrophages in bone modeling, remodeling, and fracture healing processes.