Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles (2023 edition).

Qing Zhao; Tong Wang; Hongbin Wang; Peng Cao; Chengyu Jiang; Hongzhi Qiao; Lihua Peng; Xingdong Lin; Yunyao Jiang; Honglei Jin; Huantian Zhang; Shengpeng Wang; Yang Wang; Ying Wang; Xi Chen; Junbing Fan; Bo LI; Geng LI; Bifeng Liu; Zhiyang LI; Suhua QI; Mingzhen Zhang; Jianjian Zheng; Jiuyao Zhou; Lei Zheng; Kewei Zhao

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Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles (2023 edition).

Author: Qing ZHAO ¹ ; Tong WANG ² ; Hongbin WANG ³ ; Peng CAO ⁴ ; Chengyu JIANG ⁵ ; Hongzhi QIAO ⁴ ; Lihua PENG ⁶ ; Xingdong LIN ¹ ; Yunyao JIANG ⁷ ; Honglei JIN ³ ; Huantian ZHANG ⁸ ; Shengpeng WANG ⁹ ; Yang WANG ¹⁰ ; Ying WANG ¹¹ ; Xi CHEN ¹² ; Junbing FAN ¹¹ ; Bo LI ¹³ ; Geng LI ¹⁴ ; Bifeng LIU ¹⁵ ; Zhiyang LI ¹⁶ ; Suhua QI ¹⁷ ; Mingzhen ZHANG ¹⁸ ; Jianjian ZHENG ¹⁹ ; Jiuyao ZHOU ³ ; Lei ZHENG ¹³ ; Kewei ZHAO ¹
Author Information

1. Guangdong Engineering Research Center of Chinese Herbal Vesicles, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510378, China.
2. Institute of Life and Health Engineering, the First Affiliated Hospital, Jinan University, Guangzhou 510630, China.
3. School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
4. College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210046, China.
5. Institute of Basic Medicine, Chinese Academy of Medical Sciences, Beijing 100005, China.
6. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310030, China.
7. School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China.
8. Department of Bone and Joint Surgery, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
9. State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Aomen 999078, China.
10. Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China.
11. School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
12. School of Life Sciences, Nanjing University, Nanjing 210008, China.
13. Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
14. Laboratory Animal Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
15. College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
16. Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing 210008, China.
17. School of Medical and Technology, Xuzhou Medical University, Xuzhou 221004, China.
18. School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an 710065, China.
19. The First Affiliated Hospital of Wenzhou Medical University, WenZhou 325035, China.
Publication Type:Review
Keywords: Chinese herbal medicine; consensus; extracellular vesicles; research application
From: Chinese Herbal Medicines 2024;16(1):3-12
CountryChina
Language:English
Abstract: To promote the development of extracellular vesicles of herbal medicine especially the establishment of standardization, led by the National Expert Committee on Research and Application of Chinese Herbal Vesicles, research experts in the field of herbal medicine and extracellular vesicles were invited nationwide with the support of the Expert Committee on Research and Application of Chinese Herbal Vesicles, Professional Committee on Extracellular Vesicle Research and Application, Chinese Society of Research Hospitals and the Guangdong Engineering Research Center of Chinese Herbal Vesicles. Based on the collation of relevant literature, we have adopted the Delphi method, the consensus meeting method combined with the nominal group method to form a discussion draft of "Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles (2023)". The first draft was discussed in online and offline meetings on October 12, 14, November 2, 2022 and April and May 2023 on the current status of research, nomenclature, isolation methods, quality standards and research applications of extracellular vesicles of Chinese herbal medicines, and 13 consensus opinions were finally formed. At the Third Academic Conference on Research and Application of Chinese Herbal Vesicles, held on May 26, 2023, Kewei Zhao, convenor of the consensus, presented and read the consensus to the experts of the Expert Committee on Research and Application of Chinese Herbal Vesicles. The consensus highlights the characteristics and advantages of Chinese medicine, inherits the essence, and keeps the righteousness and innovation, aiming to provide a reference for colleagues engaged in research and application of Chinese herbal vesicles at home and abroad, decode the mystery behind Chinese herbal vesicles together, establish a safe, effective and controllable accurate Chinese herbal vesicle prevention and treatment system, and build a bridge for Chinese medicine to the world.