Lymphatic vessels, miRNAs, and CAR T cells in tumor immunology.
- Author:
Xinguo JIANG
1
Author Information
- Publication Type:Review
- Keywords: Lymphatic; MicroRNA; Chimera antigen receptor T cell; Immunology; Immune therapy
- MeSH: Humans; Immunotherapy, Adoptive/methods*; Lymphatic Vessels/physiology*; MicroRNAs/physiology*; Neoplasms/therapy*; Receptors, Chimeric Antigen/immunology*; T-Lymphocytes/immunology*
- From: Journal of Zhejiang University. Science. B 2020;21(1):1-2
- CountryChina
- Language:English
- Abstract: This special feature contains three review articles that summarize recent advances pertaining to tumor immunobiology. Normalization of antitumor immunity through checkpoint inhibitors has achieved significant clinical success and benefited many cancer patients. However, not all cancer patients respond to these treatments, and among the responders, some may develop resistance and others may suffer autoimmunity that requires intervention. Tumor immunotherapy holds promise for further improving the survival of cancer patients, but deeper understanding of immunological networks that regulate anti- and pro-tumor immunity is needed. The review papers collected in this issue cover a few topics that may stimulate future interest in the relevant research field.
