Difference in survival between right- versus left-sided colorectal neuroendocrine neoplasms.

Ge-han XU; Hua-wei Zou; Ashley B Grossman

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Difference in survival between right- versus left-sided colorectal neuroendocrine neoplasms.

Author: Ge-Han XU ¹ ; Hua-Wei ZOU ² ; Ashley B GROSSMAN ³
Author Information

1. The Second Clinical College of China Medical University, Shenyang 110004, China.
2. 1st Department of Oncology, Shengjing Hospital Affiliated to China Medical University, Shenyang 110022, China.
3. NET Unit, ENETS Centre of Excellence, Royal Free Hospital, London NW3 2QG, UK.
Publication Type:Journal Article
Keywords: Acrolein; Reactive carbonyl species; Ferulic acid; Cytotoxicity; Oxidative stress
MeSH: Adult; Aged; Colorectal Neoplasms/mortality*; Female; Humans; Male; Middle Aged; Neuroendocrine Tumors/mortality*; Proportional Hazards Models; SEER Program
From: Journal of Zhejiang University. Science. B 2019;20(11):933-939
CountryChina
Language:English
Abstract: Neuroendocrine neoplasms (NENs) are a heterogeneous group of tumors that arise from neuroendocrine cells, and in some cases are capable of producing agents that may cause characteristic hormonal syndromes (Cives and Strosberg, 2018). Such tumors were previously thought to be rare, but the rate of detection of NENs, especially from the gastrointestinal tract, is increasing with the widespread use of colonoscopy, cross-sectional imaging, and biomarkers (Gu et al., 2019). A study based on the Surveillance, Epidemiology, and End Results (SEER) database showed that the age-adjusted incidence of NENs increased 6.4-fold from 1973 (1.09 per 100 000) to 2012 (6.98 per 100 000) (Dasari et al., 2017), while there was a progressive increase in the incidence of colorectal NENs (Starzyńska et al., 2017).