Three-vessel coronary artery disease may predict changes in biochemical brain injury markers after off-pump coronary artery bypass grafting<sup></sup>.

Wojciech Pawliszak; Krzysztof Szwed; Artur Słomka; Natalia Piekuś-słomka; Magdalena Szwed; Mariusz Kowalewski; Ewa Żekanowska; Alina Borkowska

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Three-vessel coronary artery disease may predict changes in biochemical brain injury markers after off-pump coronary artery bypass grafting.

Author: Wojciech PAWLISZAK ¹ ; Krzysztof SZWED ² ; Artur SŁOMKA ³ ; Natalia PIEKUŚ-SŁOMKA ⁴ ; Magdalena SZWED ² ; Mariusz KOWALEWSKI ⁵ ; Ewa ŻEKANOWSKA ³ ; Alina BORKOWSKA ²
Author Information

1. Department of Cardiac Surgery, Nicolaus Copernicus University in Toruń, Ludwik Rydygier Collegium Medicum in Bydgoszcz, 85-635 Bydgoszcz, Poland.
2. Department of Clinical Neuropsychology, Nicolaus Copernicus University in Toruń, Ludwik Rydygier Collegium Medicum in Bydgoszcz, 85-635 Bydgoszcz, Poland.
3. Department of Pathophysiology, Nicolaus Copernicus University in Toruń, Ludwik Rydygier Collegium Medicum in Bydgoszcz, 85-635 Bydgoszcz, Poland.
4. Department of Inorganic and Analytical Chemistry, Nicolaus Copernicus University in Toruń, Ludwik Rydygier Collegium Medicum in Bydgoszcz, 85-635 Bydgoszcz, Poland.
5. Clinical Department of Cardiac Surgery, Central Clinical Hospital of the Ministry of Interior in Warsaw, 02-507 Warsaw, Poland.
Publication Type:Observational Study
Keywords: Cardiac surgery; Coronary artery disease; Glial fibrillary acidic protein; Neuroserpin; Phosphorylated axonal neurofilament subunit H
MeSH: Aged; Coronary Angiography; Coronary Artery Bypass, Off-Pump/adverse effects*; Coronary Artery Disease/surgery*; Female; Glial Fibrillary Acidic Protein/blood*; Humans; Male; Middle Aged; Neurofilament Proteins/blood*; Neuropeptides/blood*; Phosphorylation; Prospective Studies; Serpins/blood*; Neuroserpin
From: Journal of Zhejiang University. Science. B 2018;19(9):735-738
CountryChina
Language:English
Abstract: Neurological injury is a frequent and important complication of coronary artery bypass grafting (CABG). Several risk factors for this type of sequela have been identified, among them aortic arch atherosclerosis. Our previous study indicated that atherosclerotic burden in coronary arteries may likewise predict postoperative neurological complications (Pawliszak et al., 2016b). We assessed the severity of this condition by using the SYNTAX score calculator. However, diagnosing angiographic three-vessel coronary artery disease (3VD) could be an even simpler method of achieving this goal.