Advances in Phytochemistry and Modern Pharmacology of Saposhnikovia Divaricata (Turcz.) Schischk.
10.1007/s11655-023-3746-5
- Author:
Jun-Wen GAO
1
;
Yang ZHAN
2
;
Yun-He WANG
3
;
Shu-Jie ZHAO
4
;
Zhong-Ming HAN
3
Author Information
1. College of Resources and Environment, Jilin Agricultural University, Changchun, 130118, China.
2. Information Center, Jilin Agricultural University, Changchun, 130118, China.
3. College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, 130118, China.
4. College of Resources and Environment, Jilin Agricultural University, Changchun, 130118, China. zhsjlong@163.com.
- Publication Type:Review
- Keywords:
Chinese herbal medicine;
Saposhnikovia divaricata (Turcz.) Schischk;
chromones;
coumarin;
pharmacological activity;
review
- MeSH:
Drugs, Chinese Herbal/pharmacology*;
Coumarins/pharmacology*;
Apiaceae/chemistry*;
Chromones
- From:
Chinese journal of integrative medicine
2023;29(11):1033-1044
- CountryChina
- Language:English
-
Abstract:
Saposhnikovia divaricata (Turcz.) Schischk (S. divaricata, Fangfeng) is a herb in the Apiaceae family, and its root has been used since the Western Han Dynasty (202 B.C.). Chromones and coumarins are the pharmacologically active substances in S. divaricata. Modern phytochemical and pharmacological studies have demonstrated their antipyretic, analgesic, anti-inflammatory, antioxidant, anti-tumor, and anticoagulant activities. Technological and analytical strategy theory advancements have yielded novel results; however, most investigations have been limited to the main active substances-chromones and coumarins. Hence, we reviewed studies related to the chemical composition and pharmacological activity of S. divaricata, analyzed the developing trends and challenges, and proposed that research should focus on components' synergistic effects. We also suggested that, the structure-effect relationship should be prioritized in advanced research.
