In Vitro Degradation Behavior of Absorbable Interface Screws.
10.3969/j.issn.1671-7104.2023.06.002
- Author:
Xuezhen ZHU
1
;
Weizhi LIU
1
;
Zhenlong SUN
1
;
Shunjie YAN
1
;
Hua LIU
2
;
Zhongli WANG
2
Author Information
1. Weigao Group Co. Ltd., National Engineering Research Center, Weihai, 264210.
2. Shandong Weigao Orthopedic Materials Co. Ltd., Weihai, 264200.
- Publication Type:Journal Article
- Keywords:
absorbable;
in vitro degradation;
interface screw;
performance study
- MeSH:
Humans;
Polyesters;
Materials Testing;
Calcium Phosphates;
Absorbable Implants
- From:Chinese Journal of Medical Instrumentation
2023;47(6):598-601
- CountryChina
- Language:Chinese
-
Abstract:
The composite material PLGA compounded with β-tricalcium phosphate (β-TCP) was prepared by melt blending method, and the absorbable interface screw was prepared by injection molding process. Prepare PBS buffer that simulates human body, conduct in vitro degradation experiments on interface screws according to relevant national and industry standards, then test and characterize interface screws at different time points for degradation of intrinsic viscosity, average molecular weight distribution, mass loss, mechanical properties and thermal properties. According to the degradation performance-time curve, determine the time node at which the interface screw loses the mechanical properties. In this paper, the in vitro degradation behavior of interfacial screws prepared from PLGA and β-TCP composites was studied in detail, providing a reference and basis for the degradation behavior of absorbable products prepared from PLGA and β-TCP composites.
