A case of chlorpropamide-induced photosensitivity.
- Author:
Jin Soo KANG
;
Tae Heung KIM
- Publication Type:Original Article
- Keywords:
Chlorpropamide;
Photosensitivity Reaction;
Leukomelanoder na
- MeSH:
Aged;
Chlorpropamide;
Eating;
Follow-Up Studies;
Humans;
Skin
- From:Korean Journal of Dermatology
1993;31(5):788-791
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of a photosensitivity reaction in a 76-year-old inale induced by chlorpropamide ingestion. The patient had erythematous scaly patches on the sur. -exposed areas, A phototest revealed the decreased minimal erythemal dose(MED) to UVA(5J/cm). A photopatch test and photo-scartch test with 1% chlorpropamide ointment and 0.1% chlorpropamic!e .olution were all negative. An oral provocation test was performed, which showed a positive result with marked decrease of MED to UVA (5J/cm). After the cessation of chlorpropamide, his skin lesions were improved markedly with complete loss of photosensitivity. Macular hypopigmentations (leukcme.anoderma) appeared on the previous erythematous patchy ereas, but disappeared during the follow-up period.
