Recent Advances and Controversies in Minute Pulmonary Meningothelial-like Nodules.
10.3779/j.issn.1009-3419.2023.102.30
- Author:
Haochen LI
1
;
Jianchao XUE
1
;
Pan LI
2
;
Yuan XU
1
;
Zhibo ZHENG
1
;
Shanqing LI
1
;
Naixin LIANG
1
Author Information
1. Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and
Peking Union Medical College, Beijing 100730, China.
2. Department of Pathology, Peking Union Medical College Hospital,
Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Meningiomas;
Minute pulmonary meningothelial-like nodules;
Multiple primary lung cancer
- From:
Chinese Journal of Lung Cancer
2023;26(8):621-629
- CountryChina
- Language:Chinese
-
Abstract:
Minute pulmonary meningothelial-like nodules (MPMNs) are benign small lesions in the lungs, with similar pathological characteristics to the meningeal epithelium. MPMNs have similar imaging manifestations to malignant tumors, which can lead to misdiagnosis in clinical practice. There is no consensus on the pathogenesis of MPMNs, with some suggest that MPMNs derive from reactive proliferation, while others suggest that MPMNs share a common origin and molecular mechanism with meningiomas in the central nervous system. Understanding the characteristics of MPMNs and studying their pathogenesis will help improve the understanding and diagnosis of MPMNs. In this article, we reviewed the clinical, pathological, imaging characteristics, differential diagnosis and pathogenesis of MPMNs. We also analyze the existing research advances regarding the pathogenesis and propose prospects for further research.
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